Saccharomyces cerevisiae (S288c)

YFH1

L000003525, YDL120W

Mitochondrial matrix iron chaperone; oxidizes and stores iron; interacts with Isu1p to promote Fe-S cluster assembly; mutation results in multiple Fe/S-dependent enzyme deficiencies; human frataxin homolog is mutated in Friedrich's ataxia

GO Process (3)

GO Function (3)

GO Component (2)

Gene Ontology Biological Process

cellular iron ion homeostasis [IDA, IGI, IMP]

glutathione metabolic process [IMP]

iron-sulfur cluster assembly [IDA, IGI, IMP, IPI]

Gene Ontology Molecular Function

ferrous iron binding [IDA]
ferroxidase activity [IDA]
iron chaperone activity [IDA, IGI]

Gene Ontology Cellular Component

mitochondrial matrix [IDA]

mitochondrion [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31943

559292

Interactors 112
Interactions 168
Network

Result Summary

YFH1

Gene Ontology Biological Process

Gene Ontology Molecular Function

ferrous iron binding [IDA]ferroxidase activity [IDA]iron chaperone activity [IDA, IGI]

Gene Ontology Cellular Component

ferrous iron binding [IDA]
ferroxidase activity [IDA]
iron chaperone activity [IDA, IGI]