Saccharomyces cerevisiae (S288c)
GET3
ARR4, guanine nucleotide exchange factor GET3, YDL100C
Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; functions as a chaperone under ATP-depleted oxidative stress conditions; subunit of the GET complex, which is involved in ATP dependent Golgi to ER trafficking and insertion of tail-anchored (TA) proteins into the ER membrane under non-stress conditions; has low-level ATPase activity; protein abundance increases in response to DNA replication stress
GO Process (7)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- ATP-independent chaperone mediated protein folding [IDA]
- pheromone-dependent signal transduction involved in conjugation with cellular fusion [IMP]
- posttranslational protein targeting to membrane [IDA]
- protein insertion into ER membrane [IMP]
- response to heat [IMP]
- response to metal ion [IMP]
- retrograde vesicle-mediated transport, Golgi to ER [IDA, IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
31962
559292
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- Interactors 490
- Interactions 1,000
- Network
- PTM Sites 10