Saccharomyces cerevisiae (S288c)

PMT1

dolichyl-phosphate-mannose-protein mannosyltransferase PMT1, L000001458, YDL095W

Protein O-mannosyltransferase of the ER membrane; transfers mannose from dolichyl phosphate-D-mannose to protein serine and threonine residues; 1 of 7 related proteins involved in O-glycosylation which is essential for cell wall rigidity; involved in ER quality control; amino terminus faces cytoplasm, carboxyl terminus faces ER lumen

GO Process (4)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

ER-associated misfolded protein catabolic process [IGI, IMP]

protein O-linked mannosylation [IDA, IGI, IMP]

protein exit from endoplasmic reticulum [IGI]

regulation of endoplasmic reticulum unfolded protein response [IGI, IMP]

Gene Ontology Molecular Function

dolichyl-phosphate-mannose-protein mannosyltransferase activity [IDA, IGI, IMP]

Gene Ontology Cellular Component

dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex [IDA, IPI]

dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex [IDA]

integral component of membrane [ISM]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31966

559292

Interactors 248
Interactions 448
Network
PTM Sites 4