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Saccharomyces cerevisiae (S288c)

SUB2

ATP-dependent RNA helicase SUB2, L000004574, YDL084W

Component of the TREX complex required for nuclear mRNA export; member of the DEAD-box RNA helicase superfamily and is involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56; relocalizes from nucleus to cytoplasm upon DNA replication stress

GO Process (6)

GO Function (1)

GO Component (5)

Gene Ontology Biological Process

chromatin silencing at telomere [IMP]

mRNA 3'-end processing [IMP]

mRNA export from nucleus [IDA, IMP, IPI]

mRNA splicing, via spliceosome [IMP]

transcription elongation from RNA polymerase II promoter [IMP]

transcription-coupled nucleotide-excision repair [IMP]

Gene Ontology Molecular Function

ATP-dependent RNA helicase activity [IGI, ISA]

Gene Ontology Cellular Component

chromosome, telomeric region [IPI]

cytoplasm [IDA]

spliceosomal complex [TAS]

transcription export complex [IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

31977

559292

Interactors 303
Interactions 453
Network
PTM Sites 13