Saccharomyces cerevisiae (S288c)

TSC13

trans-2-enoyl-CoA reductase (NADPH) TSC13, YDL015C
Enoyl reductase; catalyzes the last step in each cycle of very long chain fatty acid elongation; localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions; coimmunoprecipitates with elongases Fen1p and Sur4p; protein increases in abundance and relative distribution to ER foci increases upon DNA replication stress
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  • Interactors 411
  • Interactions 456
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  • PTM Sites 2