Saccharomyces cerevisiae (S288c)

GRX6

glutathione-disulfide reductase GRX6, YDL010W

Cis-golgi localized monothiol glutaredoxin, binds Fe-S cluster; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; GRX6 has a paralog, GRX7, that arose from the whole genome duplication

GO Process (1)

GO Function (4)

GO Component (6)

Gene Ontology Biological Process

cellular response to oxidative stress [IEP, IGI, IMP]

Gene Ontology Molecular Function

2 iron, 2 sulfur cluster binding [IDA]
glutathione-disulfide reductase activity [IDA, IMP]
iron ion binding [IDA]
protein homodimerization activity [IDA]

Gene Ontology Cellular Component

Golgi apparatus [IDA]

Golgi lumen [IDA]

cis-Golgi network [IDA]

endoplasmic reticulum membrane [IDA]

fungal-type vacuole [IDA]

integral component of membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32043

559292

Interactors 54
Interactions 58
Network
PTM Sites 2

Result Summary

GRX6

Gene Ontology Biological Process

Gene Ontology Molecular Function

2 iron, 2 sulfur cluster binding [IDA]glutathione-disulfide reductase activity [IDA, IMP]iron ion binding [IDA]protein homodimerization activity [IDA]

Gene Ontology Cellular Component

2 iron, 2 sulfur cluster binding [IDA]
glutathione-disulfide reductase activity [IDA, IMP]
iron ion binding [IDA]
protein homodimerization activity [IDA]