Saccharomyces cerevisiae (S288c)

MED2

L000003914, YDL005C

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; relocalizes to the cytosol in response to hypoxia

GO Process (3)

GO Function (2)

GO Component (4)

Gene Ontology Biological Process

RNA polymerase II transcriptional preinitiation complex assembly [IDA]

negative regulation of transcription from RNA polymerase II promoter [IPI]

positive regulation of transcription from RNA polymerase II promoter [IDA]

Gene Ontology Molecular Function

RNA polymerase II repressing transcription factor binding [IPI]
RNA polymerase II transcription factor recruiting transcription factor activity [IMP]

Gene Ontology Cellular Component

core mediator complex [IDA]

cytosol [IDA]

mediator complex [IDA]

nucleus [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32049

559292

Interactors 153
Interactions 266
Network
PTM Sites 4

Result Summary

MED2

Gene Ontology Biological Process

Gene Ontology Molecular Function

RNA polymerase II repressing transcription factor binding [IPI]RNA polymerase II transcription factor recruiting transcription factor activity [IMP]

Gene Ontology Cellular Component

RNA polymerase II repressing transcription factor binding [IPI]
RNA polymerase II transcription factor recruiting transcription factor activity [IMP]