Saccharomyces cerevisiae (S288c)

TPI1

triose-phosphate isomerase TPI1, L000002326, YDR050C
Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region; inhibition of Tpi1p activity by PEP (phosphoenolpyruvate) stimulates redox metabolism in respiring cells; E104D mutation in human TPI causes a rare autosomal disease
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32104
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  • Interactors 134
  • Interactions 148
  • Network
  • PTM Sites 26