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Saccharomyces cerevisiae (S288c)

YOS9

YDR057W

ER quality-control lectin; integral subunit of the HRD ligase; participates in efficient ER retention of misfolded proteins by recognizing them and delivering them to Hrd1p; binds to glycans with terminal alpha-1,6 linked mannose on misfolded N-glycosylated proteins and participates in targeting proteins to ERAD; member of the OS-9 protein family

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

ER-associated ubiquitin-dependent protein catabolic process [IMP]

endoplasmic reticulum unfolded protein response [IMP]

retrograde protein transport, ER to cytosol [IMP]

Gene Ontology Molecular Function

oligosaccharide binding [IDA]

Gene Ontology Cellular Component

Hrd1p ubiquitin ligase ERAD-L complex [IPI]

endoplasmic reticulum lumen [IDA]

luminal surveillance complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32110

559292

Interactors 137
Interactions 197
Network
PTM Sites 8