Saccharomyces cerevisiae (S288c)

HPR1

TRF1, L000000808, YDR138W

Subunit of THO/TREX complexes; this complex couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p

GO Process (6)

GO Function (2)

GO Component (4)

Gene Ontology Biological Process

DNA recombination [IMP]

cellular response to DNA damage stimulus [IMP]

mRNA 3'-end processing [IMP]

mRNA export from nucleus [IGI, IMP]

transcription elongation from RNA polymerase II promoter [IMP]

transcription-coupled nucleotide-excision repair [IMP]

Gene Ontology Molecular Function

nucleic acid binding [IDA]
protein complex scaffold [IMP]

Gene Ontology Cellular Component

Cdc73/Paf1 complex [IPI]

THO complex part of transcription export complex [IMP, IPI]

chromosome, telomeric region [IDA]

nucleoplasmic THO complex [IMP, IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32192

559292

Interactors 183
Interactions 387
Network
PTM Sites 23

Result Summary

HPR1

Gene Ontology Biological Process

Gene Ontology Molecular Function

nucleic acid binding [IDA]protein complex scaffold [IMP]

Gene Ontology Cellular Component

nucleic acid binding [IDA]
protein complex scaffold [IMP]