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Saccharomyces cerevisiae (S288c)

GCD6

L000000674, YDR211W

Catalytic epsilon subunit of the translation initiation factor eIF2B; eIF2B is the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression; forms cytoplasmic foci upon DNA replication stress

GO Process (1)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

regulation of translational initiation [IDA, IGI, IPI]

Gene Ontology Molecular Function

guanyl-nucleotide exchange factor activity [IDA, IMP]
translation initiation factor activity [IGI, IPI]

Gene Ontology Cellular Component

cytoplasm [IDA]

eukaryotic translation initiation factor 2B complex [IDA, IGI, IMP, IPI]

guanyl-nucleotide exchange factor complex [IDA, IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32265

559292

Interactors 128
Interactions 233
Network
PTM Sites 21