Saccharomyces cerevisiae (S288c)

HEL2

E3 ubiquitin-protein ligase HEL2, YDR266C
RING finger ubiquitin ligase (E3); involved in ubiquitylation and degradation of excess histones; interacts with Ubc4p and Rad53p; null mutant sensitive to hydroxyurea (HU); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; computational analysis suggests a role as a transcription factor
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  • Interactors 121
  • Interactions 156
  • Network
  • PTM Sites 38