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Saccharomyces cerevisiae (S288c)

HDA2

PLO2, YDR295C

Subunit of the HDA1 histone deacetylase complex; possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex contains Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance; relocalizes to the cytosol in response to hypoxia

GO Process (4)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

gene silencing by RNA [IMP]

gene silencing involved in chronological cell aging [IGI, IMP]

histone deacetylation [IDA, IMP]

negative regulation of transcription from RNA polymerase II promoter [IMP]

Gene Ontology Molecular Function

DNA binding [IDA]
chromatin binding [IDA]
histone deacetylase activity [IDA]

Gene Ontology Cellular Component

HDA1 complex [IDA, IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32347

559292

Interactors 376
Interactions 454
Network