Saccharomyces cerevisiae (S288c)

SRB7

MED21, SSX1, L000002754, S000029514, L000002097, YDR308C

Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p

GO Process (2)

GO Function (3)

GO Component (2)

Gene Ontology Biological Process

negative regulation of transcription from RNA polymerase II promoter [IMP]

positive regulation of transcription from RNA polymerase II promoter [IMP]

Gene Ontology Molecular Function

RNA polymerase II repressing transcription factor binding [IPI]
RNA polymerase II transcription coactivator activity [IDA]
RNA polymerase II transcription corepressor activity [IMP, IPI]

Gene Ontology Cellular Component

core mediator complex [IDA]

mediator complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32361

559292

Interactors 167
Interactions 283
Network
PTM Sites 2

Result Summary

SRB7

Gene Ontology Biological Process

Gene Ontology Molecular Function

RNA polymerase II repressing transcription factor binding [IPI]RNA polymerase II transcription coactivator activity [IDA]RNA polymerase II transcription corepressor activity [IMP, IPI]

Gene Ontology Cellular Component

RNA polymerase II repressing transcription factor binding [IPI]
RNA polymerase II transcription coactivator activity [IDA]
RNA polymerase II transcription corepressor activity [IMP, IPI]