Saccharomyces cerevisiae (S288c)

VPS74

API1, MNN3, YDR372C
Golgi phosphatidylinositol-4-kinase effector and PtdIns4P sensor; interacts with the cytosolic domains of cis and medial glycosyltransferases, and in the PtdIns4P-bound state mediates the targeting of these enzymes to the Golgi; interacts with the catalytic domain of Sac1p, the major cellular PtdIns4P phosphatase, to direct dephosphosphorylation of the Golgi pool of PtdIns4P; tetramerization required for function; ortholog of human GOLPH3/GPP34/GMx33
UBI
PHO

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB
Download 326 Published Interactions For This Protein
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  • Interactors (221)
  • Interactions (326)
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  • PTM Sites (13)