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Saccharomyces cerevisiae (S288c)

SAC7

L000001794, YDR389W

GTPase activating protein (GAP) for Rho1p; regulator of a Tor2p-mediated, Rho1p GTPase switch that controls organization of the actin cytoskeleton; negative regulator of the RHO1-PKC1-MAPK cell integrity (CWI) and membrane fluidity homeostasis signaling pathways; potential Cdc28p substrate; SAC7 has a paralog, BAG7, that arose from the whole genome duplication

GO Process (5)

GO Function (1)

GO Component (1)

Gene Ontology Biological Process

negative regulation of Rho protein signal transduction [IGI]

negative regulation of protein kinase C signaling [IGI, IMP]

positive regulation of Rho GTPase activity [IDA]

regulation of actin cytoskeleton organization [IGI]

regulation of fungal-type cell wall organization [IGI, IMP]

Gene Ontology Molecular Function

Rho GTPase activator activity [IDA]

Gene Ontology Cellular Component

cell cortex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32450

559292

Interactors 528
Interactions 769
Network
PTM Sites 22