Saccharomyces cerevisiae (S288c)
RPB7
DNA-directed RNA polymerase II subunit RPB7, B16, L000001681, YDR404C
RNA polymerase II subunit B16; forms dissociable heterodimer with Rpb4p; Rpb4/7 dissociates from RNAPII as Ser2 CTD phosphorylation increases; Rpb4/7 regulates cellular lifespan via mRNA decay process; involved in recruitment of 3'-end processing factors to transcribing RNA polymerase II complex, export of mRNA to cytoplasm under stress conditions; also involved in translation initiation
GO Process (5)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- nuclear-transcribed mRNA catabolic process, exonucleolytic [IGI]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [IMP]
- positive regulation of translational initiation [IMP]
- transcription from RNA polymerase II promoter [IGI]
- transcription initiation from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
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32464
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- Interactors 379
- Interactions 595
- Network
- PTM Sites 5