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Saccharomyces cerevisiae (S288c)

STP1

BAP1, SSY2, L000002132, YDR463W

Transcription factor; contains a N-terminal regulatory motif (RI) that acts as a cytoplasmic retention determinant and as an Asi dependent degron in the nucleus; undergoes proteolytic processing by SPS (Ssy1p-Ptr3p-Ssy5p)-sensor component Ssy5p in response to extracellular amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing; STP1 has a paralog, STP2, that arose from the whole genome duplication

GO Process (2)

GO Function (2)

GO Component (3)

Gene Ontology Biological Process

positive regulation of transcription from RNA polymerase II promoter [IGI, IMP, ISS]

positive regulation of transcription, DNA-templated [IDA]

Gene Ontology Molecular Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]

Gene Ontology Cellular Component

cytoplasm [IDA]

plasma membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32517

559292

Interactors 216
Interactions 258
Network
PTM Sites 13