Saccharomyces cerevisiae (S288c)

PDR3

AMY2, TPE2, drug-responsive transcription factor PDR3, L000002985, L000001363, YBL005W
Transcriptional activator of the pleiotropic drug resistance network; regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting PDRE sites (PDR responsive elements); post-translationally up-regulated in cells lacking functional mitochondrial genome; involved in diauxic shift; relative distribution to nucleus increases upon DNA replication stress; APCC(Cdh1) substrate; PDR3 has a paralog, PDR1, that arose from the whole genome duplication
Download Curated Data for this Protein
32694
559292
Switch View:
  • Interactors 111
  • Interactions 141
  • Network
  • PTM Sites 4