Saccharomyces cerevisiae (S288c)
PDR3
AMY2, TPE2, drug-responsive transcription factor PDR3, L000002985, L000001363, YBL005W
Transcriptional activator of the pleiotropic drug resistance network; regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting PDRE sites (PDR responsive elements); post-translationally up-regulated in cells lacking functional mitochondrial genome; involved in diauxic shift; relative distribution to nucleus increases upon DNA replication stress; APCC(Cdh1) substrate; PDR3 has a paralog, PDR1, that arose from the whole genome duplication
GO Process (2)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Download Curated Data for this Protein
32694
559292
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- Interactors 111
- Interactions 141
- Network
- PTM Sites 4