Saccharomyces cerevisiae (S288c)

KAP104

L000003444, YBR017C

Transportin or cytosolic karyopherin beta 2; functions in the rg-nuclear localization signal-mediated nuclear import/reimport of mRNA-binding proteins Nab2p and Hrp1p; regulates asymmetric protein synthesis in daughter cells during mitosis

GO Process (4)

GO Function (1)

GO Component (4)

Gene Ontology Biological Process

exit from mitosis [IMP]

mRNA-binding (hnRNP) protein import into nucleus [IDA, IMP, IPI]

protein import into nucleus [IMP, IPI]

transcription factor import into nucleus [IMP, IPI]

Gene Ontology Molecular Function

nuclear localization sequence binding [IPI]

Gene Ontology Cellular Component

cellular bud neck [IDA]

cellular bud tip [IDA]

cytosol [IDA]

integral component of membrane [ISM]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32720

559292

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Interactors 272
Interactions 324
Network
PTM Sites 6

Sites with Multi-PTMs

Displaying 1 protein 1 non-assigned with 6 total post translational modifications

Sort By: [Default] [Alphabetical] [PTM count] [Length] [Status]

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NP_009573

Kap104p

Length: 918

1
MASTWKPAED YVLQLATLLQ NCMSPNPEIR NNAMEAMENF QLQPEFLNYL
51
CYILIEGESD DVLKQHYSLQ DLQNNRATAG MLLKNSMLGG NNLIKSNSHD
101
LGYVKSNIIH GLYNSNNNLV SNVTGIVITT LFSTYYRQHR DDPTGLQMLY
151
QLLELTSNGN EPSIKALSKI MEDSAQFFQL EWSGNTKPME ALLDSFFRFI
201
SNPNFSPVIR SESVKCINTV IPLQTQSFIV RLDKFLEIIF QLAQNDENDL
251
VRAQICISFS FLLEFRPDKL VSHLDGIVQF MLHLITTVNE EKVAIEACEF
301
LHAFATSPNI PEHILQPYVK DIVPILLSKM VYNEESIVLL EASNDDDAFL
351
EDKDEDIKPI APRIVKKKEA GNGEDADDNE DDDDDDDDED GDVDTQWNLR
401
KCSAATLDVM TNILPHQVMD IAFPFLREHL GSDRWFIREA TILALGAMAE
451
GGMKYFNDGL PALIPFLVEQ LNDKWAPVRK MTCWTLSRFS PWILQDHTEF
501
LIPVLEPIIN TLMDKKKDVQ EAAISSVAVF IENADSELVE TLFYSQLLTS
551
FDKCLKYYKK KNLIILYDAI GRFAEKCALD ETAMQIILPP LIEKWALLSD
601
SDKELWPLLE CLSCVASSLG ERFMPMAPEV YNRAFRILCH CVELEAKSHQ
651
DPTIVVPEKD FIITSLDLID GLVQGLGAHS QDLLFPQGTK DLTILKIMLE
701
CLQDPVHEVR QSCFALLGDI VYFFNSELVI GNLEDFLKLI GTEIMHNDDS
751
DGTPAVINAI WALGLISERI DLNTYIIDMS RIILDLFTTN TQIVDSSVME
801
NLSVTIGKMG LTHPEVFSSG AFANDSNWNK WCLSVNALDD VEEKSSAYMG
851
FLKIINLTST EVTMSNDTIH KIVTGLSSNV EANVFAQEIY TFLMNHSAQI
901
SAINFTPDEI SFLQQFTS

Location	PTM	Residue	Source(s)	Note(s)
95	Ubiquitination	K	Mayor T (2007)	-
105	Ubiquitination	K	Mayor T (2007)	-
561	Ubiquitination	K	Mayor T (2007)	-
808	Ubiquitination	K	Mayor T (2007)	-
830	Ubiquitination	K	Mayor T (2007)	-

View

Non-Assigned PTMs

Post translational modifications that are currently unassigned to a specific residue location.

Location	PTM	Residue	Source(s)	Note(s)
-	Ubiquitination	K	Duttler S (2013)	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
			Kolawa NJ (2013)	eyJOT1RFUyI6WyJUYWJsZSBTMTsgVmFsaWQgU3Vic3RyYXRlIiwibGlrZWx5IHViaXF1aXRpbiBjb25qdWdhdGUiXSwiUkVMQVRJT05TSElQUyI6eyJVQkk0IjoiPHNwYW4+PGEgaHJlZj0naHR0cHM6XC9cL3RoZWJpb2dyaWQub3JnXC8zMTIxNVwvc3VtbWFyeVwvc2FjY2hhcm9teWNlcy1jZXJldmlzaWFlXC91Ymk0Lmh0bWwnIGFsdD0nVUJJNCc+VUJJNDxcL2E+PFwvc3Bhbj4ifX0=
			Mayor T (2007)	eyJOT1RFUyI6WyJsaWtlbHkgdWJpcXVpdGluIGNvbmp1Z2F0ZSJdLCJSRUxBVElPTlNISVBTIjp7IlVCSTQiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMxMjE1XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL3ViaTQuaHRtbCcgYWx0PSdVQkk0Jz5VQkk0PFwvYT48XC9zcGFuPiJ9fQ==
			Peng J (2003)	eyJOT1RFUyI6WyJDYW5kaWRhdGUgdWJpcXVpdGluLWNvbmp1Z2F0ZWQgcHJvdGVpbnMgbGlzdGVkIGluIHN1cHBsZW1lbnRhcnkgdGFibGUgMSBvZiB0aGUgcGFwZXIuIl0sIlJFTEFUSU9OU0hJUFMiOnsiVUJJNCI6IjxzcGFuPjxhIGhyZWY9J2h0dHBzOlwvXC90aGViaW9ncmlkLm9yZ1wvMzEyMTVcL3N1bW1hcnlcL3NhY2NoYXJvbXljZXMtY2VyZXZpc2lhZVwvdWJpNC5odG1sJyBhbHQ9J1VCSTQnPlVCSTQ8XC9hPjxcL3NwYW4+In19
			Ziv I (2011)	eyJSRUxBVElPTlNISVBTIjp7IlVCSTQiOiI8c3Bhbj48YSBocmVmPSdodHRwczpcL1wvdGhlYmlvZ3JpZC5vcmdcLzMxMjE1XC9zdW1tYXJ5XC9zYWNjaGFyb215Y2VzLWNlcmV2aXNpYWVcL3ViaTQuaHRtbCcgYWx0PSdVQkk0Jz5VQkk0PFwvYT48XC9zcGFuPiJ9fQ==

Relationships

Protein	Relationship	Location	PTM	Residue	Identity	Source(s)
UBI4	Conjugate	-	Ubiquitination	K	PTM	Duttler S (2013)
						Kolawa NJ (2013)
						Mayor T (2007)
						Peng J (2003)
						Ziv I (2011)

Result Summary