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Saccharomyces cerevisiae (S288c)

NHP6B

YBR090C-A, L000001246, YBR089C-A

High-mobility group (HMG) protein; binds to and remodels nucleosomes; involved in recruiting FACT and other chromatin remodelling complexes to the chromosomes; functionally redundant with Nhp6Ap; required for transcriptional initiation fidelity of some tRNA genes; homologous to mammalian HMGB1 and HMGB2; NHP6B has a paralog, NHP6A, that arose from the whole genome duplication

GO Process (4)

GO Function (3)

GO Component (1)

Gene Ontology Biological Process

RNA polymerase III transcriptional preinitiation complex assembly [IDA, IGI]

chromatin remodeling [IGI]

maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter [IDA]

transcription from RNA polymerase II promoter [IGI]

Gene Ontology Molecular Function

DNA binding, bending [IDA]
nucleosome binding [ISS]
sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32795

559292

Interactors 167
Interactions 214
Network
PTM Sites 2