Saccharomyces cerevisiae (S288c)

MMS4

SLX2, YBR100W, YBR098W

Subunit of structure-specific Mms4p-Mus81p endonuclease; cleaves branched DNA; involved in recombination, DNA repair, and joint molecule formation/resolution during meiotic recombination; phosphorylation of the non-catalytic subunit Mms4p by Cdc28p and Cdc5p during mitotic cell cycle activates the function of Mms4p-Mus81p

GO Process (6)

GO Function (2)

GO Component (2)

Gene Ontology Biological Process

DNA repair [IMP]

DNA topological change [IGI]

cellular response to DNA damage stimulus [IMP]

reciprocal meiotic recombination [IGI, IMP]

regulation of reciprocal meiotic recombination [IGI]

resolution of meiotic recombination intermediates [IGI]

Gene Ontology Molecular Function

crossover junction endodeoxyribonuclease activity [IDA]
endodeoxyribonuclease activity [IDA]

Gene Ontology Cellular Component

Holliday junction resolvase complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

32804

559292

Interactors 237
Interactions 504
Network
PTM Sites 8