Saccharomyces cerevisiae (S288c)

BSD2

L000000194, YBR290W
Heavy metal ion homeostasis protein; facilitates trafficking of Smf1p and Smf2p metal transporters to vacuole where they are degraded; acts as an adaptor protein with Rsp5p in the regulated endocytosis of Smf1p and is itself ubiquitylated by Rsp5p; controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification
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  • Interactors 215
  • Interactions 276
  • Network
  • PTM Sites 6