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Saccharomyces cerevisiae (S288c)

CUP2

ACE1, L000000439, YGL166W

Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations; required for regulation of copper genes in response to DNA-damaging reagents; CUP2 has a paralog, HAA1, that arose from the whole genome duplication

GO Process (2)

GO Function (3)

GO Component (1)

Gene Ontology Biological Process

regulation of transcription from RNA polymerase II promoter [IMP]

response to copper ion [IMP]

Gene Ontology Molecular Function

RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
copper ion binding [IDA]
copper ion regulated core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA, IMP]

Gene Ontology Cellular Component

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33088

559292

Interactors 91
Interactions 96
Network