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Saccharomyces cerevisiae (S288c)

AIM14

YNO1, YGL160W

NADPH oxidase localized to the perinuclear ER; produces superoxide from NADPH; overexpression causes MCA1 dependent apoptosis; likely involved in superoxide-mediated regulation of the actin cytoskeleton; member of a conserved superfamily of NADPH oxidases (NOX enzymes); has similarity to iron/copper reductases (FRE1-8), particularly Fre8p

GO Process (2)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

apoptotic process [IGI]

regulation of actin cytoskeleton organization [IMP]

Gene Ontology Molecular Function

ferric-chelate reductase activity [IMP]
oxidoreductase activity, oxidizing metal ions [ISA]
superoxide-generating NADPH oxidase activity [IMP]

Gene Ontology Cellular Component

integral component of membrane [ISM]

perinuclear endoplasmic reticulum [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33093

559292

Interactors 93
Interactions 105
Network
PTM Sites 3