Saccharomyces cerevisiae (S288c)


DNA-binding E3 ubiquitin-protein ligase SNT2, YGL131C
Subunit of Snt2C complex, RING finger ubiquitin ligase (E3); physically associates with Ecm5p and Rpd3p; along with Ecm5p, recruits Rpd3p to small number of promoters; colocalizes with Ecm5p, independently of Rpd3p, to promoters of stress response genes upon oxidative stress; involved in ubiquitylation, degradation of excess histones; interacts with Ubc4p; role in regulating genes encoding amine transporters; relocalizes from nucleus to cytoplasm upon DNA replication stress
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  • Interactors 52
  • Interactions 64
  • Network
  • PTM Sites 4