Saccharomyces cerevisiae (S288c)

VPS45

STT10, VPL28, L000002478, YGL095C

Protein of the Sec1p/Munc-18 family; essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment

GO Process (9)

GO Function (2)

GO Component (4)

Gene Ontology Biological Process

CVT pathway [IMP]

Golgi to endosome transport [IGI]

Golgi to vacuole transport [IMP]

Golgi vesicle fusion to target membrane [IMP]

positive regulation of SNARE complex assembly [IMP]

protein targeting to vacuole [IMP]

vacuolar acidification [IMP]

vacuole inheritance [IMP]

vacuole organization [IMP]

Gene Ontology Molecular Function

SNARE binding [IPI]
unfolded protein binding [IMP, IPI]

Gene Ontology Cellular Component

Golgi membrane [IDA]

SNARE complex [IPI]

cytosol [IDA]

extrinsic component of membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33156

559292

Interactors 171
Interactions 220
Network
PTM Sites 9

Result Summary

VPS45

Gene Ontology Biological Process

Gene Ontology Molecular Function

SNARE binding [IPI]unfolded protein binding [IMP, IPI]

Gene Ontology Cellular Component

SNARE binding [IPI]
unfolded protein binding [IMP, IPI]