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Saccharomyces cerevisiae (S288c)

SGF73

SCA7, YGL066W

SAGA complex subunit; has a role in anchoring the deubiquitination module into SAGA and SLIK complexes; involved in preinitiation complex assembly at promoters; relocalizes to the cytosol in response to hypoxia; human ortholog ataxin-7 is associated with spinocerebellar ataxia diseases; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay

GO Process (6)

GO Function (3)

GO Component (5)

Gene Ontology Biological Process

chromatin modification [IMP]

histone acetylation [IMP, IPI]

histone deubiquitination [IMP]

mRNA export from nucleus [IMP]

positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [IMP]

protein complex assembly [IMP]

Gene Ontology Molecular Function

enzyme activator activity [IDA, IMP]
histone acetyltransferase activity [IMP]
structural molecule activity [IGI, IMP]

Gene Ontology Cellular Component

DUBm complex [IDA]

SAGA complex [IDA, IPI]

SLIK (SAGA-like) complex [IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33181

559292

Interactors 721
Interactions 1,272
Network
PTM Sites 12