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Saccharomyces cerevisiae (S288c)

DUO1

L000004421, YGL061C

Essential subunit of the Dam1 complex (aka DASH complex); cooperates with Dam1p to connect the DASH complex with microtubules (MT); couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis

GO Process (3)

GO Function (2)

GO Component (1)

Gene Ontology Biological Process

attachment of spindle microtubules to kinetochore [IDA]

positive regulation of attachment of spindle microtubules to kinetochore [IDA]

positive regulation of microtubule polymerization [IDA]

Gene Ontology Molecular Function

microtubule binding [IDA]
microtubule plus-end binding [IDA]

Gene Ontology Cellular Component

DASH complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33186

559292

Interactors 446
Interactions 653
Network
PTM Sites 1