Saccharomyces cerevisiae (S288c)

PDR1

AMY1, ANT1, BOR2, CYH3, NRA2, SMR2, TIL1, TPE1, TPE3, drug-responsive transcription factor PDR1, L000002984, L000003503, L000001361, YGL013C
Transcription factor that regulates the pleiotropic drug response; zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes; relocalizes to the cytosol in response to hypoxia; PDR1 has a paralog, PDR3, that arose from the whole genome duplication
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  • Interactors 207
  • Interactions 295
  • Network
  • PTM Sites 9