Saccharomyces cerevisiae (S288c)

ESP1

L000000584, YGR098C
Separase, a caspase-like cysteine protease; promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p; relative distribution to the nucleus increases upon DNA replication stress
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33341
559292
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  • Interactors 590
  • Interactions 677
  • Network
  • PTM Sites 1