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Saccharomyces cerevisiae (S288c)

SYF2

NTC31, L000004196, YGR129W

Member of the NineTeen Complex (NTC); NTC contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; relocalizes to the cytosol in response to hypoxia; isy1 syf2 cells have defective spindles activiating cell cycle arrest

GO Process (1)

GO Function (2)

GO Component (7)

Gene Ontology Biological Process

mRNA splicing, via spliceosome [IMP]

Gene Ontology Molecular Function

first spliceosomal transesterification activity [IC]
second spliceosomal transesterification activity [IC]

Gene Ontology Cellular Component

Prp19 complex [IDA]

U2-type catalytic step 1 spliceosome [IDA]

U2-type catalytic step 2 spliceosome [IDA]

U2-type post-mRNA release spliceosomal complex [IDA]

U2-type prespliceosome [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33377

559292

Interactors 136
Interactions 230
Network
PTM Sites 7