Saccharomyces cerevisiae (S288c)

LSB1

YGR136W
Negative regulator of actin nucleation-promoting factor activity; interacts with Las17p, a homolog of human Wiskott-Aldrich Syndrome protein (WASP), via an N-terminal SH3 domain, and along with PIN3 cooperatively inhibits the nucleation of actin filaments; overexpression blocks receptor-mediated endocytosis; protein increases in abundance and forms nuclear foci in response to DNA replication stress; LSB1 has a paralog, PIN3, that arose from the whole genome duplication
UBI
PHO
GO Process (1)
GO Function (0)
GO Component (3)

Gene Ontology Cellular Component

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB
Download 64 Published Interactions For This Protein
33384
559292
  • Stats & Options
Switch View:
  • Interactors (44)
  • Interactions (64)
  • Network
  • PTM Sites (16)