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Saccharomyces cerevisiae (S288c)

CDC6

AAA family ATPase CDC6, L000000246, YJL194W

Essential ATP-binding protein required for DNA replication; component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p; relocalizes from nucleus to cytoplasm upon DNA replication stress

GO Process (4)

GO Function (7)

GO Component (4)

Gene Ontology Biological Process

G1/S transition of mitotic cell cycle [IMP]

pre-replicative complex assembly involved in nuclear cell cycle DNA replication [IDA, IMP]

regulation of DNA-dependent DNA replication initiation [IMP]

regulation of chromatin silencing at telomere [IMP]

Gene Ontology Molecular Function

ATP binding [IDA, IMP]
ATPase activity [IDA]
DNA replication origin binding [IDA]
GTP binding [IDA]
GTPase activity [IDA]
chromatin binding [IDA, IMP]
protein binding [IPI]

Gene Ontology Cellular Component

DNA replication preinitiation complex [IDA]

cytoplasm [IDA]

nuclear pre-replicative complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

33569

559292

Interactors 329
Interactions 549
Network
PTM Sites 12