Saccharomyces cerevisiae (S288c)

RFA3

RPA14, RPA3, L000001622, YJL173C
Subunit of heterotrimeric Replication Protein A (RPA); RPA is a highly conserved single-stranded DNA binding protein complex involved in DNA replication, repair, recombination; RPA protects against inappropriate telomere recombination, and upon telomere uncapping, prevents cell proliferation by a checkpoint-independent pathway; with Sgs1p-Top2p-Rmi1p, stimulates DNA catenation/decatenation activity of Top3p; protein abundance increases in response to DNA replication stress
Download Curated Data for this Protein
33587
559292
Switch View:
  • Interactors 176
  • Interactions 231
  • Network
  • PTM Sites 2