Saccharomyces cerevisiae (S288c)


Putative protein of unknown function; functions together with HAM1 to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA, without affecting uptake or incorporation of uracil into RNA; proposed to be involved in the metabolism of purine and pyrimidine base analogues; deletion mutants are sensitive to HAP and AHA
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  • Interactors 24
  • Interactions 26
  • Network
  • PTM Sites 4