Saccharomyces cerevisiae (S288c)

OSM1

FRDS2, L000001317, YJR051W
Fumarate reductase, catalyzes the reduction of fumarate to succinate; required for the reoxidation of intracellular NADH under anaerobic conditions; mutations cause osmotic sensitivity; has two translation start sites, one at the annotated start codon which produces an ER-targeted form required for anaerobic growth, and one at codon 32 which produces a mitochondrially-targeted form; OSM1 has a paralog, FRD1, that arose from the whole genome duplication
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  • Interactors 88
  • Interactions 120
  • Network
  • PTM Sites 3