Saccharomyces cerevisiae (S288c)

NPA3

EPA1, GPN1, GTPase NPA3, YJR072C
Member of the conserved GPN-loop GTPase family; has a role in transport of RNA polymerase II to the nucleus; exhibits GTP-dependent binding to PolII; has ATPase activity; involved in sister chromatid cohesion; phosphorylated by the Pcl1p-Pho85p kinase complex; human homolog XAB1 interacts with human RNA polymerase II; protein abundance increases in response to DNA replication stress
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  • Interactors 133
  • Interactions 204
  • Network
  • PTM Sites 16