Saccharomyces cerevisiae (S288c)


L000003362, YKL125W
Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA; structure reveals unique HEAT repeat fold and a surface serine patch; phosphorylation of serine patch impairs cell growth and reduces RNA polymerase I binding in vitro and RNA polymerase I recruitment to the rDNA gene in vivo
Download Curated Data for this Protein
Switch View:
  • Interactors 157
  • Interactions 188
  • Network
  • PTM Sites 1