Saccharomyces cerevisiae (S288c)

DEF1

VID31, DNA damage-responsive RNA polymerase-degradation factor DEF1, YKL054C

RNAPII degradation factor; forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex; mutant is deficient in Zip1p loading onto chromosomes during meiosis

UPS Project

GO Process (5)

GO Function (0)

GO Component (1)

Gene Ontology Biological Process

cellular response to DNA damage stimulus [IMP]

protein ubiquitination [IMP]

telomere maintenance [IMP]

transcription-coupled nucleotide-excision repair [IGI]

ubiquitin-dependent protein catabolic process [IDA, IMP]

Gene Ontology Cellular Component

nucleus [IMP]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34079

559292

Interactors 430
Interactions 504
Network
PTM Sites 16

Result Summary

DEF1

Gene Ontology Biological Process

Gene Ontology Cellular Component