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Saccharomyces cerevisiae (S288c)

CDC16

anaphase promoting complex subunit CDC16, L000000256, YKL022C

Subunit of the anaphase-promoting complex/cyclosome (APC/C); which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation; relocalizes to the cytosol in response to hypoxia

GO Process (3)

GO Function (1)

GO Component (3)

Gene Ontology Biological Process

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [IDA, IMP]

negative regulation of DNA-dependent DNA replication initiation [IMP]

protein ubiquitination [IDA, IMP]

Gene Ontology Molecular Function

ubiquitin-protein transferase activity [IMP]

Gene Ontology Cellular Component

anaphase-promoting complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34109

559292

Interactors 186
Interactions 438
Network
PTM Sites 9