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Saccharomyces cerevisiae (S288c)

SWD2

CPS35, SAF37, YKL018W

Subunit of the COMPASS (Set1C) histone H3K4 methyltransferase complex; required for Set1C stability and optimal activity; COMPASS methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination

GO Process (7)

GO Function (1)

GO Component (2)

Gene Ontology Biological Process

histone H3-K4 methylation [IDA]

histone H3-K79 methylation [IMP]

mRNA 3'-end processing [IMP]

snoRNA 3'-end processing [IMP]

telomere maintenance [IMP]

termination of RNA polymerase II transcription, exosome-dependent [IPI]

termination of RNA polymerase II transcription, poly(A)-coupled [IPI]

Gene Ontology Molecular Function

histone methyltransferase activity (H3-K4 specific) [IDA]

Gene Ontology Cellular Component

Set1C/COMPASS complex [IPI]

mRNA cleavage and polyadenylation specificity factor complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34114

559292

Interactors 173
Interactions 310
Network
PTM Sites 3