Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells.

Src-related cytoplasmic PTKs are physically and functionally associated with cell surface receptors and are involved in signal transduction. In this paper we report the identification of src-related proteins p59fyn, pp60c-src and p62yes in human microvascular endothelial cells cultured from normal human skin and their physical association with the thrombospondin receptor ...
CD36. Such an association represents a potential signalling pathway by which thrombospondin may regulate angiogenesis.
Mesh Terms:
Antigens, CD, Antigens, CD36, Blotting, Western, Cells, Cultured, Endothelium, Vascular, Humans, Protein-Tyrosine Kinases, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-fyn, Proto-Oncogene Proteins c-yes, Proto-Oncogene Proteins pp60(c-src), Skin, src-Family Kinases
FEBS Lett.
Date: Aug. 29, 1994
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