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Saccharomyces cerevisiae (S288c)

OSH6

oxysterol-binding protein OSH6, YKR003W

Member of an oxysterol-binding protein family; overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery; overexpression extends lifespan by promoting vacuolar fusion; OSH6 has a paralog, OSH7, that arose from the whole genome duplication

GO Process (6)

GO Function (7)

GO Component (3)

Gene Ontology Biological Process

endocytosis [IGI]

exocytosis [IGI]

maintenance of cell polarity [IGI]

sterol homeostasis [IMP]

sterol metabolic process [IGI]

sterol transport [IGI]

Gene Ontology Molecular Function

lipid binding [IDA]
oxysterol binding [ISS]
phosphatidic acid binding [IDA]
phosphatidylinositol-3,4-bisphosphate binding [IDA]
phosphatidylinositol-3,5-bisphosphate binding [IDA]
phosphatidylinositol-4-phosphate binding [IDA]
phosphatidylinositol-5-phosphate binding [IDA]

Gene Ontology Cellular Component

cortical endoplasmic reticulum [IDA]

cytoplasm [IDA]

extrinsic component of membrane [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34135

559292

Interactors 97
Interactions 107
Network
PTM Sites 4