Saccharomyces cerevisiae (S288c)

SIR1

L000001894, YKR101W

Protein involved in silencing at mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin

GO Process (2)

GO Function (2)

GO Component (1)

Gene Ontology Biological Process

chromatin silencing at silent mating-type cassette [IDA, IGI]

establishment of chromatin silencing [IMP]

Gene Ontology Molecular Function

chromatin binding [IPI]
sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

chromatin silencing complex [IDA]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34232

559292

Interactors 86
Interactions 162
Network

Result Summary

SIR1

Gene Ontology Biological Process

Gene Ontology Molecular Function

chromatin binding [IPI]sequence-specific DNA binding [IDA]

Gene Ontology Cellular Component

chromatin binding [IPI]
sequence-specific DNA binding [IDA]