Saccharomyces cerevisiae (S288c)

PAP2

TRF4, non-canonical poly(A) polymerase PAP2, L000002953, YOL115W
Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia
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  • Interactors 423
  • Interactions 566
  • Network
  • PTM Sites 4