Saccharomyces cerevisiae (S288c)

MSH2

PMS5, mismatch repair ATPase MSH2, L000001190, YOL090W
Protein that binds to DNA mismatches; forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity and involved in interstrand cross-link repair; Msh2p-Msh6p binds to and hydrolyzes ATP
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  • Interactors 345
  • Interactions 624
  • Network
  • PTM Sites 3