Saccharomyces cerevisiae (S288c)

DNL4

LIG4, DNA ligase (ATP) DNL4, L000003479, YOR005C
DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome
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34408
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  • Interactors 259
  • Interactions 288
  • Network
  • PTM Sites 3