Saccharomyces cerevisiae (S288c)
DNL4
LIG4, DNA ligase (ATP) DNL4, L000003479, YOR005C
DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome
GO Process (3)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
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34408
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- Interactors 259
- Interactions 288
- Network
- PTM Sites 3