Saccharomyces cerevisiae (S288c)

AUS1

ATP-binding cassette sterol transporter AUS1, YOR011W
Plasma membrane sterol transporter of the ATP-binding cassette family; required, along with Pdr11p, for uptake of exogenous sterols and their incorporation into the plasma membrane; activity is stimulated by phosphatidylserine; sterol uptake is required for anaerobic growth because sterol biosynthesis requires oxygen; AUS1 has a paralog, PDR11, that arose from the whole genome duplication
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34416
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  • Interactors 91
  • Interactions 96
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