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Saccharomyces cerevisiae (S288c)

HIR2

SPT1, L000000777, YOR038C

Subunit of HIR nucleosome assembly complex; involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p; relocalizes to the cytosol in response to hypoxia

GO Process (3)

GO Function (3)

GO Component (3)

Gene Ontology Biological Process

DNA replication-independent nucleosome assembly [IDA]

negative regulation of transcription from RNA polymerase II promoter [IDA]

transcription elongation from RNA polymerase II promoter [IGI]

Gene Ontology Molecular Function

DNA binding [IDA]
nucleosome binding [IMP]
transcription corepressor activity [IDA]

Gene Ontology Cellular Component

HIR complex [IDA, IPI]

SGD Alliance of Genome Resources Entrez Gene RefSeq UniprotKB

Download Curated Data for this Protein

34440

559292

Interactors 459
Interactions 754
Network
PTM Sites 7